Regina Hexaphone more or less got started back in the Summer of 1997. Chris happened to hear some songs Sara recorded at Jerry Kee's Duck-Kee studio in Mebane, NC, and soon after approached her about getting together to play some music. After a couple of months of sporadically rehearsing as a duo in Chris' living room, they were asked to contribute a song to the Third Place Coffeehouse's "Local Honey" compilation CD. "Every Traveler's Song" was recorded at Duck-Kee in September 1997, and featured Jerry (ex-Dish) on drums and Brian Sliwa (ex-Motocaster) on guitar.

Time passed and the inevitable occured: Regina Hexaphone was asked to play in public. Zeke agreed to play drums, Greg Humphreys (Hobex) sat in on slide guitar, and proto-Regina Hexaphone debuted at the Cave in Chapel Hill in late December 1997. Six months and a few more shows later, Margaret joined in, and the first full-fledged incarnation of Regina Hexaphone debuted at Aly and Beth Khalifa's July 4th party in 1998.

tracks
In the summer of 1998, the band recorded and contributed a song ("Mary Don't You Weep") to American Primitve Recordings' Day Before Yesterday compilation CD. A few other Regina Hexaphone songs recorded at Duck-Kee in January 1999, and with Anders Parker (Varnaline) in 2000-2001, can be found at the duckonbike.com web site. "Eleven Songs," a CD recorded and mixed with Anders and Jerry is more or less out of print. Regina Hexaphone has songs on two compilation discs released in 2004: "Topsy Turvy" on "I Can't Get that Evil Weiner Song Out of My Head" (Hypno-Vista) and "Old Friend" on "Hoss" (Waylon Jennings tribute). Finally, and at long last, the first proper Regina Hexahone album, The Beautiful World, was released on the band's own Erie Recordings in June 2004.

players
Members of Regina Hexaphone have been and continue to be musically active with myriad area bands. Sara has played her many stringed instruments with Shark Quest and the Angels of Epistemology (Merge); Dish (Interscope); blackgirls (Mammoth); and Dana and Karen Kletter (Rykodisc/Hannibal). Chris has also wielded brushes and plucked bass strings with the Kletter sisters, as well as with Benighted Maestro and the Bettys. He also currently plays bass with Clay Merritt and plays guitar and sings in the Management. Margaret's violin and bass have formerly transported the Starry Wisdom Band, the Carbines (Oil Rig), and the Comas (Plastique). She also currently plays with North Elementary  and has toured extensively with Sparklehorse, the Frames, Cat Power, and Belle and Sebastian. Former drummer Zeke Hutchins was once the percussive force behind Queen Sarah Saturday (Thirsty Ear) and now backs up Tift Merritt (Lost Highway), as well as playing in Stillhouse. Current drummer Jerry Kee played with Sara in Dish and with Chris in the Bettys (along with countless other projects), and now plays with Chris in the Management as well as in his own band, the Feebles. New organist Nathan Brown played guitar in the laramie uk and the first incarnation of star city.